Is Vancomycin Ototoxicity a Significant Risk?
نویسندگان
چکیده
منابع مشابه
Is Vancomycin Ototoxicity a Significant Risk?
Forouzesh and colleagues recently reported an increase in vancomycin ototoxicity in parallel with the increasing use of higher vancomycin doses (4). The report suggests an overall incidence of vancomycin-induced ototoxicity of 12%, doubling historic estimates (3). This is a surprisingly high estimate for a drug that many experts do not consider to be ototoxic (5, 6). The authors have outlined s...
متن کاملIs vancomycin ototoxicity a significant risk?
Forouzesh and colleagues recently reported an increase in vancomycin ototoxicity in parallel with the increasing use of higher vancomycin doses (4). The report suggests an overall incidence of vancomycin-induced ototoxicity of 12%, doubling historic estimates (3). This is a surprisingly high estimate for a drug that many experts do not consider to be ototoxic (5, 6). The authors have outlined s...
متن کاملVancomycin ototoxicity: a reevaluation in an era of increasing doses.
Nephrotoxicity and ototoxicity have historically been documented as relatively rare complications of vancomycin monotherapy. Recent reports have linked aggressive vancomycin dosing strategies to significant risks of nephrotoxicity. We evaluated the rate of high-frequency hearing loss detected by audiometry for patients on vancomycin therapy. For this purpose, we used retrospective case-control ...
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PURPOSE Aminoglycoside-induced deafness caused by mutations in the mitochondrial 12S ribosomal RNA gene has been described in a number of Asian patients. The purpose of the current study is to analyze ethnically diverse patients in the United States with hearing loss after aminoglycoside exposure for presence or absence of these mitochondrial DNA mutations, and establish the frequency and clini...
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The aim of the study was to assess the outcomes of grandmultiparous women receiving the current obstetric care in Maternity Hospital Kuala Lumpur. Recent data regarding some of the complications are conflicting and the significance of grandmultiparity is now in question. Therefore, a retrospective cohort study of 237 grandmultiparous and 254 multiparous women were undertaken. Chi-squared and t ...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2009
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.00537-09